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MDRO

Decoding Resistance, Architecting Salvage

We specialize in decoding the molecular mechanisms of resistance to architect effective “salvage” therapies. Our approach moves beyond standard sensitivity testing to understand the genetic drivers of resistance.

  • Resistant Gram-Negatives: advanced protocols for CRE (Carbapenem-resistant Enterobacteriaceae) and pan-drug resistant Acinetobacter.
  • Enzymatic Profiling: molecular tests to differentiate NDM, KPC, and OXA-48-like enzymes for the appropriate beta-lactamase inhibitor.
  • Synergy Interpretation: guidance on high-dose prolonged infusions and synergistic drug combinations (e.g. Ceftazidime-Avibactam plus Aztreonam).
Microbiology lab work